The genus name Aenigma may refer to:

  • Animalia:
    • Aenigma Newman, 1836 ( Coleoptera, Carabidae)
    • Aenigma Kuznetsova, 1957 (Ostracoda) = Kuznetsoviella Doweld, 2016
    • Aenigma Koch, 1846 (Mollusca, Anomiidae) = Enigmonia Iredale, 1918
    • Aenigma Strecker, 1876 ( Lepidoptera)
    • Aenigma Karsch, 1878 (Arachnida, Miturgidae) = Argoctenus Karsch, 1878
    • Aenigma Amsel, 1856 (Lepidoptera)
    • Aenigma Omelko, 1988 (Lepidoptera)
  • Plantae:
    • Aenigma H.A.Keller, Lilloa 54(1): 59, (2017), nom. illeg. (Apocynaceae) = synonym of Topea H.A.Keller, Bonplandia (Corrientes) 26: 134. (2017)
    • Aenigma (Luer) Szlach. & Kolan., Diversity (Basel) 14(5)-372: 23 (2022), nom. illeg. = synonym of Andinia (Luer) Luer (Orchidaceae)